All body tissues with the passage of time lose support and structure due to the loss of collagen production, at the facial level this manifests itself with flaccidity, thin, rough and stiff skin. The objective of biostimulants is to improve the production and quality of collagen to recover firmness. Among the most commonly used biostimulants are polycaprolactone (Ellansé) and hyaluronic acid (Profhilo). These treatments are ideal for application on skin, fatty tissue and ligaments. They are used on face, neck and hands.